Brand Name Entocort Enema Common Name budesonide enema
The content of this page:
How does this medication work? What will it do for me?
Budesonide belongs to the class of medications called glucocorticosteroids. Budesonide enemas are used to treat diseases caused by inflammation of the colon and rectum, such as certain types of ulcerative colitis that involve the rectum, sigmoid, and descending colon. It works within the colon and rectum to decrease inflammation.
How should I use this medication?
The usual adult dose of budesonide enema is the contents of one 115 mL enema nightly, at bedtime, for 4 weeks. If necessary, the treatment period may be lengthened to 8 weeks.
To prepare the medication:
- Remove the nozzle from the bottle, leaving the protective cap on.
- Remove a tablet from the aluminum foil pack and put it into the bottle.
- Replace the nozzle on the bottle, making sure that the protective cap is on firmly.
- Shake the bottle vigorously for at least 10 seconds, or until the tablet has dissolved. The liquid will be slightly yellow in colour.
- After preparation, the budesonide enema should be used immediately.
To use the medication:
- Lie on your left side, shake the bottle well, and grasp the bottle at the neck where it is most rigid.
- Expose the tip of the bottle by removing the protective cap.
- Carefully insert the lubricated tip into the rectum.
- Slowly squeeze the container until empty.
- Remove the tip from the rectum.
- Roll over on your stomach and stay in this position for at least 5 minutes, to allow enough time for the medication to coat the colon.
- Retain the enema as long as possible, preferably the whole night.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is important to use this medication exactly as prescribed by your doctor.
If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
What form(s) does this medication come in?
Each budesonide enema 0.02 mg/mL consists of 2 components: a dispersible tablet and an applicator bottle of vehicle solution.
Each dispersible tablet contains 2.3 mg of micronized budesonide. Nonmedicinal ingredients: colloidal silicon dioxide, lactose, lactose anhydrous, magnesium stearate, cross-linked polyvidone, and riboflavin-5-phosphate sodium.
The vehicle is a solution containing methylparaben, propylparaben, sodium chloride, and purified water.
Who should NOT take this medication?
Do not use this medication if you:
- are allergic to budesonide or any ingredients of the medication
- have complications in the area of the digestive tract where this medication is effective (e.g., bowel perforation, possibility of bowel obstruction, abscess or fistulae)
- have any active bacterial, fungal, or viral infections
- have active tuberculosis infection
What side effects are possible with this medication?
- skin rash
Stop taking the medication and seek immediate medical attention if any of the following occur:
- signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
Are there any other precautions or warnings for this medication?
General precautions: Advise all doctors involved in your care that you have been using this medication. If you have been taking "cortisone" tablets, your doctor may want you to discontinue the tablet form of the medication. Much less corticosteroid is absorbed from budesonide enemas, so stopping the tablets should be done gradually to reduce the likelihood of withdrawal symptoms such as tiredness, headache, nausea, or vomiting.
Medical conditions: People with diabetes, glaucoma, liver disease, osteoporosis, or stomach ulcers should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Severe bowel disease: People with severe ulcerative disease of the bowel should use this medication with caution, as they are susceptible to perforation of the bowel wall. If you have severe ulcerative disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Stopping medication: Stopping this medication suddenly may cause symptoms of the illness to return. Do not stop using this medication abruptly without checking with your doctor first.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while using this medication, contact your doctor immediately.
Breastfeeding: This medication passes into breast milk. If you are a breast-feeding mother and are using budesonide enemas, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of budesonide enemas have not been established for children.
What other drugs could interact with this medication?
There may be an interaction between budesonide and any of the following:
- abiraterone acetate
- "azole" antifungals (e.g., itraconazole, ketoconazole, voriconazole)
- calcium channel blockers (e.g., amlodipine, diltiazem, nifedipine, verapamil)
- grapefruit juice
- HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs; e.g., delaviridine, efavirenz, etravirine, nevirapine)
- HIV protease inhibitors (e.g., atazanavir, indinavir, ritonavir, saquinavir)
- macrolide antibiotics (e.g., clarithromycin, erythromycin)
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
All material copyright MediResource Inc. 1996 – 2018. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Entocort-Enema