Brand Name Lansoprazole by Sivem Common Name lansoprazole
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How does this medication work? What will it do for me?Lansoprazole belongs to the family of medications called proton pump inhibitors (PPIs). These medications slow or prevent the production of acid within the stomach.
Lansoprazole is used to treat gastric (stomach) ulcers, duodenal (intestinal) ulcers, reflux esophagitis, and gastroesophageal reflux disease (GERD). It is also used in combination with antibiotics to treat and eradicate H. pylori bacteria (a major cause of duodenal ulcers).
Lansoprazole is used to treat gastric ulcers caused by a family of pain relievers known as nonsteroidal anti-inflammatory drugs (NSAIDs), and to reduce the risk of gastric ulcers for people who are taking NSAIDs. It is also used to treat conditions associated with the over-production of stomach acid, including Zollinger-Ellison syndrome.
How should I use this medication?
To treat duodenal (intestinal) ulcers, the recommended adult dose of lansoprazole is 15 mg daily, before breakfast, for 2 to 4 weeks. For duodenal ulcers that return, lansoprazole may be used for up to one year.
To treat gastric (stomach) ulcers, the recommended adult dose of lansoprazole is 15 mg daily, before breakfast, for 4 to 8 weeks. The usual recommended dose to treat gastric ulcers caused by NSAIDs is 15 mg to 30 mg daily, before breakfast, for up to 8 weeks. When used to reduce the risk of gastric ulcers for people who are taking NSAIDs, the usual dose is 15 mg daily, before breakfast, for up to 12 weeks.
To treat duodenal ulcers caused by H. pylori bacteria (as confirmed by a test), the recommended dose of lansoprazole is 30 mg along with clarithromycin 500 mg and amoxicillin 1,000 mg, all taken twice daily for 7, 10, or 14 days. All of these medications should be taken before meals. This combination of medications helps kill the bacteria that can cause duodenal ulcers.
To treat GERD and associated heartburn symptoms, the recommended dose of lansoprazole is 15 mg daily before breakfast for up to 8 weeks. Doses up to 30 mg daily are sometimes prescribed for reflux esophagitis or other conditions associated with increased secretion of acid by the stomach.
To treat GERD in children 1 to 11 years of age, the recommended dose is 15 mg to 30 mg (depending on the child's weight) once daily for up to 12 weeks. An increase in dose may be beneficial for some children. For adolescents 12 to 17 years old who have GERD, the adult dose can be used.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
Lansoprazole should be taken before breakfast or, if taken twice daily, before breakfast and another meal. The medication should not be crushed or chewed. The capsules should be swallowed whole with a glass of water. People who have difficulty swallowing capsules may open the capsule and sprinkle its contents on a tablespoon of applesauce, which should then be immediately swallowed.
Lanzoprazole tablets should not be chewed; they should be placed on the tongue for about one minute to allow the tablet to dissolve. Once the tablet has dissolved, the particles can be swallowed.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
What form(s) does this medication come in?
Each pink cap-green body capsule imprinted with "15" in white ink on the body and containing white-to-off-white pellets, contains 15 mg lansoprazole. Nonmedicinal ingredients: D&C Yellow No. 10, FD&C Green No. 3, FD&C Red No. 3, gelatin, hydroxypropyl cellulose, hypromellose, macrogols, maize starch, magnesium carbonate, methacrylic acid-ethyl acrylate copolymer, polysorbate 80, silica colloidal anhydrous, sucrose, sugar spheres, talc, and titanium dioxide.
Each pink cap-black body capsule imprinted with "30" in white ink on the body and containing white-to-off-white pellets, contains 30 mg lansoprazole. Nonmedicinal ingredients: D&C Yellow No. 10, FD&C Green No. 3, FD&C Blue No. 1, gelatin, hydroxypropyl cellulose, hypromellose, macrogols, maize starch, magnesium carbonate, methacrylic acid-ethyl acrylate copolymer, polysorbate 80, silica colloidal anhydrous, sucrose, sugar spheres, talc, and titanium dioxide.
Who should NOT take this medication?
Do not take lansoprazole if you are allergic to lansoprazole or any ingredients of the medication.
What side effects are possible with this medication?
- dry mouth
- flu-like symptoms
Check with your doctor as soon as possible if any of the following side effects occur:
- abdominal pain
- joint or muscle pain
- pain or burning while urinating
- signs of liver damage, e.g.:
- abdominal pain
- brown urine
- light-coloured stools
- loss of appetite
- yellowing of skin or whites of eyes
- sinus pain
- skin rash
- sore throat
- vision or hearing changes
Stop taking the medication and seek immediate medical attention if any of the following occur:
- chest pain
- signs of a serious allergic reaction (swelling of face or throat, hives, or difficulty breathing)
- signs of a severe skin reaction, e.g.:
- high fever
- painful blisters on the skin, mouth, or eyes
- skin peeling off
Are there any other precautions or warnings for this medication?
Before you begin taking a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take this medication.
Diarrhea: When gastric acid is decreased, the number of bacteria normally in the digestive system increases. Occasionally, this can cause serious infection in the digestive tract. If you experience severe watery or bloody diarrhea, fever, or abdominal pain while taking lansoprazole, contact your doctor as soon as possible.
Electrolyte balance: Long term use of lansoprazole may cause the levels of electrolytes such as magnesium, calcium and potassium in the blood to decrease. If you experience symptoms of fluid and electrolyte imbalance such as muscle pains or cramps; dry mouth; numb hands, feet, or lips; or racing heartbeat, contact your doctor as soon as possible. Your doctor may do blood tests periodically to monitor the levels of these electrolytes in your blood while you are taking this medication.
Liver function: If you have reduced liver function or liver disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Methotrexate interaction: Lansoprazole, like other medications in this group, may interact with methotrexate when the two medications are used at the same time. This combination may lead to higher than expected amounts of methotrexate in the body and can cause serious side effects, including kidney damage, irregular heartbeat, anemia, or infection. If you take lansoprazole and are also going to receive a dose of methotrexate, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
More serious conditions of the stomach and intestines: If you experience symptoms of a more serious condition of the stomach and intestines (e.g., trouble swallowing, unplanned weight loss, vomiting of blood or food, or black stools) while taking this medication, contact your doctor immediately.
Osteoporosis fractures: Long term use of lansoprazole may be related to an increased risk of bone fractures in the hip, wrist or spine, as a result of weakened bones. This risk is further increased if you are at risk of developing osteoporosis. If you have osteoporosis or have risk factors for developing osteoporosis, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Pregnancy: There are no adequate or well-controlled studies on the use of this medication by pregnant women. This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if lansoprazole passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of this medication have not been established for use by children under one year old. For children 1 to 17 years of age, this medication can be used to treat GERD for a maximum of 12 weeks.
What other drugs could interact with this medication?
There may be an interaction between lansoprazole and any of the following:
- "azole" antifungals (e.g., itraconazole, ketoconazole, posaconazole)
- bisphosphonates (e.g., alendronate, risedronate)
- HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs; e.g., delaviridine, efavirenz, etravirine, nevirapine)
- HIV protease inhibitors (e.g., atazanavir, indinavir, ritonavir, saquinavir)
- iron salts
- multivitamins with minerals
- St. John's wort
- "statin" anti-cholesterol medications (e.g., atorvastatin, lovastatin, simvastatin)
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
All material copyright MediResource Inc. 1996 – 2018. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Lansoprazole-by-Sivem