Brand Name Nu-Fenofibrate Common Name fenofibrate
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How does this medication work? What will it do for me?
Fenofibrate belongs to the class of medications known as fibrates. It is used in addition to diet and exercise to treat high cholesterol.
Fenofibrate reduces bad cholesterol (low-density lipoproteins [LDL] and very-low-density lipoproteins [VLDL]) and triglycerides in your blood. It also increases good cholesterol (high-density lipoprotein [HDL]) levels. Reduction of cholesterol levels in the blood has been shown to reduce the risks associated with heart disease, such as heart attack.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
How should I use this medication?
The usual adult dose of fenofibrate is 300 mg per day. The 100 mg capsules are taken as one capsule three times daily with plenty of fluid, with or after a meal.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Nu-Fenofibrate is no longer being manufactured for sale in Canada. For brands that may still be available, search under fenofibrate. This article is being kept available for reference purposes only. If you are using this medication, speak with your doctor or pharmacist for information about your treatment options.
Who should NOT take this medication?
Fenofibrate should not be taken by anyone who:
- is allergic to fenofibrate or to any of the ingredients of the medication
- is allergic to other medications of the fibrate class (e.g., gemfibrozil, bezafibrate, clofibrate)
- has had a "sunburn" type reaction after taking any fibrate medication or ketoprofen
- is pregnant or breast-feeding
- has a disorder known as type 1 hyperlipoproteinemia
- has severe liver disease, kidney disease, or gallbladder disease
- has pancreatitis
- is taking "statin" cholesterol medications and have risks for developing muscle problems
What side effects are possible with this medication?
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
- red, itchy skin
- skin rash
- stomach pain
Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- signs of a blood clot in the arm or leg (tenderness, pain, swelling, warmth, or redness in the arm or leg) or lungs (difficulty breathing, sharp chest pain that is worse when breathing in, coughing, coughing up blood, sweating, or passing out)
- signs of liver problems (e.g., dark urine, general feeling of being unwell, loss of appetite, nausea, vomiting, or yellowing of the eyes or skin)
- unexplained muscle pain, tenderness, weakness, chills, or fever
Stop taking the medication and seek immediate medical attention if any of the following occur:
- signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
- signs of pancreatitis (e.g., abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, swollen abdomen, severe stomach pain, nausea, or vomiting)
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Are there any other precautions or warnings for this medication?
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Combination therapy: The use of fenofibrate and "statin" medications (e.g., atorvastatin, lovastatin, simvastatin) at the same time may increase the risk of side effects. Talk to your doctor about the risks and benefits of taking the two types of medications together.
Gallbladder disease: Fenofibrate may cause gallstones to form in some people. If you have a history of gallstones or gallbladder disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Kidney disease: Kidney disease or decreased kidney function can cause this medication to build up in the body, causing side effects. If you have kidney problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Liver function: People taking fenofibrate may have changes in liver function that produce abnormal liver test results. Your doctor will recommend regular liver tests while you are taking this medication. If you have severe changes in liver function, your doctor may recommend that you take a lower dose of this medication or stop taking it altogether.
Pancreatitis: Fenofibrate can cause the pancreas to become inflamed. If you have a history of pancreatitis, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Report signs of pancreatitis such as abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, or swollen abdomen to your doctor immediately.
Muscle effects: On rare occasions, muscle damage has been associated with the use of fenofibrate, usually in people with reduced kidney function. You should contact your doctor as soon as possible if you notice unexplained muscle pain, tenderness, or weakness, particularly if you also have malaise (general feeling of illness) or fever.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if fenofibrate passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of this medication have not been established for use by children.
Seniors: Seniors are more likely to have reduced kidney function and may need lower doses of this medication.
What other drugs could interact with this medication?
There may be an interaction between fenofibrate and any of the following:
- cholestyramine resin
- "statin" medications (e.g., atorvastatin, lovastatin, simvastatin)
- sulfonylureas (e.g., gliclazide, glyburide, tolbutamide)
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 – 2019. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Nu-Fenofibrate