|Enter drug name|
|Search by First Letter|
|A B C D E F G H I J K L M N O P Q R S T U V W X Y Z|
polymyxin b - neomycin topical compound
How does this medication work? What will it do for me?
Polymyxin b - neomycin compound belongs to the family of medications known as antibacterials. The compound contains a combination of antibiotics used to treat certain types of infections caused by bacteria.
The topical ointment can be used to treat some skin infections and to prevent infections in burns, minor cuts, and wounds. The drops are used to treat some types of infections of the eye and ear. The irrigating solution is used to prevent bladder infections in people who have catheters in place.
All preparations work by killing the bacteria that cause these infections.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.
What form(s) does this medication come in?
Each mL of sterile, aqueous solution contains neomycin (as sulfate, 57 mg) 40 mg, polymyxin B (as sulfate) 200,000 units. Nonmedicinal ingredients: methylparaben, sulfuric acid, and/or sodium hydroxide, as pH adjusters. Not for injection.
Each g contains polymyxin B sulfate 5000 units, bacitracin zinc 400 units, and neomycin sulfate 5 mg, in a low melting point petrolatum base.
Except for Neosporin irrigating solution - for which dilution is required for administration - dilution of Neosporin is not recommended; reduction of the antibiotic concentrations may reduce their therapeutic efficacy.
How should I use this medication?
Eye and ear drops: The suggested dose is 1 or 2 drops in the affected eye or ear 2 to 4 times daily, or more frequently as directed by your doctor. Avoid contaminating the dropper by touching it with the fingers, eyes, ears, or other surfaces. Do not wear contact lenses during eye treatment.
Eye ointment: Apply a thin ribbon of ointment into the lower lid of the eye as directed by your doctor.
Irrigating solution: Your doctor or health care professional will administer the irrigating solution.
Topical ointment: Apply a small quantity 2 to 5 times a day over the affected area. Cover with a dressing or leave exposed as directed by your doctor. Do not use in the eyes.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
This medication should not be used for more than 7 days without medical supervision.
It is important to use medication exactly as prescribed by your doctor. If you miss a dose, use it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Who should NOT take this medication?
Polymyxin - neomycin compound should not be used by anyone who:
- is allergic to polymyxin b, neomycin, gramicidin, or to any of the ingredients of the medication
- is allergic to any other medications in the class of medications known as aminoglycosides (e.g., gentamicin)
- is using the drop solution for the ear where perforation of the tympanic membrane is known or suspected and in long-standing cases of chronic otitis media (middle ear infection)
- is using the drops in the eye during surgical procedures or before surgery in circumstances where the product could gain access to the fluids in the eye
- is younger than 2 years of age
- has preexisting nerve deafness
- may experience absorption into the bloodstream from the bladder irrigation solution (e.g., has an erosion of the bladder wall)
- would use it in large quantities or on large areas for long periods of time or in circumstances where the medication may be absorbed into the body
What side effects are possible with this medication?
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
- itching, pain, skin rash, swelling, redness, or other sign of skin irritation not present before use of this medication
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- a wound or lesion that does not heal
- itching, swelling, or redness of the eye not present before starting the medication
- loss of hearing
- signs of an allergic reaction such as worsening eczema with red, scaly, swollen, itchy skin
- stinging and burning in the inner ear
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Are there any other precautions or warnings for this medication?
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Absorption: Neomycin can cause damage to the ears or kidneys if it is absorbed into the body. When using polymyxin b - neomycin compound on large areas of the skin, such as when treating extensive burns or ulceration, discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Allergic reactions: Polymyxin b - neomycin compound may cause the area being treated to become more sensitive. If you experience itching, dry skin, reddening, and swelling of the area being treated or if a lesion or wound is not healing, stop using this medication and contact your doctor.
Contact lenses: Avoid wearing contact lenses if you are using the eye solution.
Length of treatment: This medication should not be used for more than 7 days without medical supervision. Prolonged use of this medication may cause overgrowth of other bacteria or fungi. Contact your doctor if you do not see improvement after one week of treatment or if your condition worsens.
For eye infections, treatment should be continued until at least 48 hours after the eye has apparently recovered.
After treatment with polymyxin b - neomycin compound, this medication should not be used again for at least 3 months to reduce the possibility of bacteria becoming resistant to the medication and experiencing more severe adverse effects of the medication.
Ointment: The ointment should not be used in the eyes or in the external ear canal if the eardrum is perforated.
Pregnancy: This medication should not be used during pregnancy. If you become pregnant while using this medication, stop using it and contact your doctor.
Breast-feeding: It is not known if polymyxin b - neomycin compound passes into breast milk. If you are a breast-feeding mother and are using this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children younger than 2 years of age.
What other drugs could interact with this medication?
There may be an interaction between polymyxin - neomycin compound and any of the following:
- neuromuscular blocking agents (e.g., tubocurarine, pancuronium)
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material © 1996-2013 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
Did you find this article interesting? Recommend it to a friend!